Research Article

Clinical Significance of Epigenetic Inactivation of hMLH1 and BRCA1 in Tunisian Patients with Invasive Breast Carcinoma

Table 4

Correlation between p53 expression level and double negative (ER-/PR-, ER-/HER2- ) and triple negative (ER-/PR-/HER2-) breast cancer.

N ER-/PR- ER-/HER2- ER-/PR-/HER2-

YesNoYesNoYesNo
P53
Positive1610 (62.5%)6 (37.5%)8 (50%)8 (50%)7 (43.8%)9 (56.3%)
Negative233 (13%)20 (87%)3 (13%) 20 (87%)2 (8.7%)21 (91.3%)
P (t-test) .001 .011 .01