BioMed Research International / 2009 / Article / Tab 2

Research Article

Variable Increased Expression of Program Death-1 and Program Death-1 Ligands on Peripheral Mononuclear Cells Is Not Impaired in Patients with Systemic Lupus Erythematosus

Table 2

Enhancement on IFN-γ production by blockage of PD-1 or PD-1 ligands.

Blocking AbsNormal ( ) Mean ± SD (%)*SLE ( ) Mean ± SD (%) value

Anti-PD-1156 ± 270294 ± 658.731
Anti-PDL1243 ± 174271 ± 623.836
Anti-PDL2191 ± 197397 ± 333.755
Anti-PDL1+Anti-PDL2177 ± 156189 ± 665.876

* These percentages refer to change over baseline of IgG-treated PBMCs.

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