BioMed Research International / 2009 / Article / Tab 3

Research Article

Variable Increased Expression of Program Death-1 and Program Death-1 Ligands on Peripheral Mononuclear Cells Is Not Impaired in Patients with Systemic Lupus Erythematosus

Table 3

Enhancement on IL-2 production by blockage of PD-1 or PD-1 ligands.

Blocking AbsNormal ( ) Mean ± SD (%)*SLE ( ) Mean ± SD (%) value

Anti-PD-1141 ± 161193 ± 224.645
Anti-PDL1134 ± 201190 ± 188.721
Anti-PDL2160 ± 272153 ± 216.879
Anti-PDL1+Anti-PDL2143 ± 206203 ± 212.879

* These percentages refer to change over baseline of IgG-treated PBMCs.

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