BioMed Research International / 2009 / Article / Fig 2

Research Article

Inhibitory Effect of Flavonoids on the Efflux of 𝑁 -Acetyl 5-Aminosalicylic Acid Intracellularly Formed in Caco-2 Cells

Figure 2

(a) The time course curve of N-acetyl 5-aminosalicylic acid in Caco-2 cells, (b) the medium and (c) the total, and (d) the cellular accumulation percent. Caco-2 cells grown in tissue culture dishes were incubated with 200  M 5-ASA for 1, 2, and 4 hours in the absence (white-circle) and the presence of quercetin (black-circle), fisetin (square), and morin (triangle) at the concentration of 100  M. Cell 5-AcASA (%): (cells/cells plus medium) 100. Each point represents the mean SD of four to five experiments. Significant difference from control * , ** .

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