Inhibitory Effect of Flavonoids on the Efflux of -Acetyl 5-Aminosalicylic Acid Intracellularly Formed in Caco-2 Cells
Figure 2
(a) The time course curve of N-acetyl 5-aminosalicylic acid in Caco-2 cells, (b) the medium and (c) the total, and (d) the cellular accumulation percent. Caco-2 cells grown in tissue culture dishes were incubated with 200 M 5-ASA for 1, 2, and 4 hours in the absence () and the presence of quercetin (), fisetin (), and morin () at the concentration of 100 M. Cell 5-AcASA (%): (cells/cells plus medium) 100. Each point represents the mean SD of four to five experiments. Significant difference from control *, **.
) and the presence of quercetin (
), fisetin (
), and morin (
) at the concentration of 100 M. Cell 5-AcASA (%): (cells/cells plus medium) 100. Each point represents the mean SD of four to five experiments. Significant difference from control *, **.
