Oxaprozin-Induced Apoptosis on CD40 Ligand-Treated Human Primary Monocytes Is Associated with the Modulation of Defined Intracellular Pathways
Figure 5
(a) CD40L-induced monocyte survival is associated with Akt, ERK 1/2, P38 MAPK and NF-B activation, and caspase 3 inhibition. (b) Oxaprozin-induced apoptosis in CD40L-treated monocytes is associated with the inhibition of Akt and NF-B and the activation of caspase 3 pathways.
