Functional Characterization of N-Terminally GFP-Tagged GLP-1 Receptor

Table 1

Effect of GLP-1(7-36)amide on GLP-1 receptor binding sites from Rin m5F cells and CHO cells transiently expressing human GLP-1 receptor and GFP-GLP-1 receptor.

	IC50 (nM)	Bmax (receptor/cell)
GLP-1 receptor from CHO cells	18.2±0.8	102500±1700
GFP-GLP-1 receptor from CHO cells	8.9±3.8	1830±220
Endogenous GLP-1 receptor from Rin m5F cells	0.56±0.02	1107±121