Research Article

Identification of IbeR as a Stationary-Phase Regulator in Meningitic Escherichia coli K1 that Carries a Loss-of-Function Mutation in rpoS

Table 3

Identification of differentially displayed proteins in 2D maps.

Spot numberProtein IDAccess numberMass(KD)/PI (theriol)Mass(KD)/PI (analytic)Peptides matchedSequence coverageFunction category


downregulated

D1dihydrolipoamide dehydrogenase (LpdA)gi 1579980050.9/5.7951.0/6.0524947%Central metabolism (CM): E3 component of pyruvate dehydrogenase complex
D2tryptophanase (TnaA)gi 1580430553.8/5.8849.0/6.109234%Response to environmental modifications (REMs), and CM: initiation of indole signaling
D3outer membrane protein C (OmpC)gi 1580276840.5/4.5540.5/4.555350%REM: osmotically regulated porin
D4outer membrane protein C (OmpC)gi 1580276840.5/4.5540.5/4.60720%REM: osmotically regulated porin

upregulated

U1elongation factor EF-Tu (TufB)gi 1580385243.4/5.343.5/5.305545%REM: binding and transport of aminoacyl-tRNA
U2glyceraldehyde-3-phosphate (G-3P) dehydrogenase A(GapA)gi 1580219335.7/6.6136.0/6.209432%CM: oxidation and phosphorylation of G-3P to 1,3-bisphosphoglycerate
U3outer membrane protein 3a (OmpA)gi 1580081637.3/5.9930.0/5.803548%REM: maintaining cell envelope integrity
U4alkyl hydroperoxide reductase(AhpC)gi 1580032020.9/5.0322.0/5.155749%REM: a primary scavenger of endogenous H2O2 at a low (10−5 M) concentration