An Evolutionary Perspective of Animal MicroRNAs and Their Targets
The number of predicted conserved miRNA target sites. (a) Predicted number of conserved targets, conserved target sites and poorly conserved sites of human miRNAs (based on TargetScanS). (b) The number of predicted conserved miRNA targets was divided according to the conservation level of the miRNA itself (H, Human; P, Chimp; M, Mouse; R, Rat; D, Dog; C, Chicken; based on TargetScanS). Shaded in red/green are the regions with the largest/least number of targets (resp.). Extreme numbers of targets are boxed and are discussed in the text.
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