Pyrrolidine Dithiocarbamate Attenuates Paraquat-Induced Lung Injury in Rats

Table 1

Comparisons of GSH-Px, SOD, and MDA among groups of PQ treatment, PQ+PDTC treatment, and the control (Mean ± SE).

Animal group	𝑛	Sacrifice	GSH-Px (U/mL)		SOD (U/mL)		MDA (nmol/mgprot)
		Time (𝑑)	Blood plasma	BALF	Blood plasma	BALF	Blood plasma	BALF
control	6	0	5147.60±94.34	60.28±13.86	288.62±2.88	59.51±21.60	1.09±0.22	0.46±0.30
PQ	5	3	4456.57±122.10^∗∗	18.99±5.20^∗∗	100.95±3.74^∗∗	10.12±2.72^∗∗	3.27±1.51^∗	1.76±0.30^∗
treatment	6	7	4194.06±154.30^∗∗	11.28±2.43^∗∗	99.93±0.34^∗∗	12.49±10.89^∗∗	3.21±0.12^∗∗	0.76±0.20^∗
	6	14	3907.14±465.88^∗∗	24.71±10.39^∗∗	275.73±20.24	42.11±8.80	0.87±0.07	0.61±0.04
	6	21	4655.24±291.08^∗∗	42.67±14.94	285.37±10.57	70.58±5.54	0.32±0.06^∗∗	0.16±0.02^∗
PQ + PDTC treatment	5	3	4735.35±188.20▲ ∗∗	19.39±4.80^∗∗	102.13±2.63^∗∗	18.28±6.48^∗∗	2.74±0.08^∗∗	0.90±0.50▲ ▲∗
	6	7	4384.16±91.93▲ ∗∗	18.61±8.18^∗∗	103.45±0.98▲ ▲∗∗	15.53±5.49^∗∗	2.38±0.40▲ ▲∗∗	0.71±0.44
	6	14	4307.14±21.43^∗∗	43.95±8.61▲ ▲∗	322.49±22.85▲ ▲∗	61.08±10.34▲ ▲	0.30±0.01▲ ▲∗∗	0.62±0.01
	6	21	5001.90±508.37	62.48±8.66▲	365.09±16.17▲ ▲∗∗	108.43±21.17▲ ▲∗∗	0.32±0.03^∗∗	0.08±0.03^∗∗

∗Compared with the control, 𝑃<.05,∗∗ 𝑃<.01, ▲ compared with the PQ treatment, 𝑃<.05, ▲ ▲  𝑃<.01.