Benefit of Whole Pelvic Radiotherapy Combined with Neoadjuvant Androgen Deprivation for the High-Risk Prostate Cancer

Table 3

Univariate and multivariate analysis of clinical and treatment factors predicting for cause specific survival (𝑛=162).

Factor	𝑃		Hazard ratio (95% confidence interval)
	Univariate*	Multivariatê‌
WPRT + N-ADT versus PORT	.01	.03	2.4 (1.5–3.1)
Age (<70 versus >70)	.23	—	—
PSA level (<30 versus >30)	.09	—	—
T stage (T2c versus T3)	.1	—	—
Gleason score (2–7 versus 8–10)	.02	.04	1.3 (1.08–2.5)
%𝑁+ (<30 versus >30)	.001	.03	2.1 (1.4–2.2)

WPRT: whole pelvic radiotherapy, N-ADT: neoadjuvant androgen deprivation therapy, PORT: prostate radiotherapy only, PSA: prostatic specific antigen, %𝑁+: probability of metastases to pelvic lymph nodes calculated according to the Roach formula [18].
*Kaplan-Meier analysis log-rank 𝑃-value.