DNA Damage/Repair and Polymorphism of the hOGG1 Gene in Lymphocytes of AMD Patients
Figure 2
Oxidative DNA damage in peripheral blood lymphocytes of 30 AMD patients (grey bars) and 30 healthy controls (white bars) recognized by Nth (a) or Fpg (b) at 1 g/mL in the alkaline comet assay. Each bar is a mean difference between Fpg or Nth treated cells and enzyme-nontreated controls. DNA damage was measured as the percentage of DNA in the tail in the alkaline comet assay. The number of cells scored for each individual was 100. The results displayed are the mean of three independent experiments ± S.E.M. .
