Bullatacin Triggered ABCB1-Overexpressing Cell Apoptosis via the Mitochondrial-Dependent Pathway
Effect of antioxidant molecules N-acetyl-l-cysteine (NAC) on ROS generation (a) and cell apoptosis (b) induced by bullatacin in KBv200 cells. KBv200 cells pretreated with 1 mmol/L NAC for 4 hours and then exposed to 10 nmol/L bullatacin for 48 hours, ROS generation and cell apoptosis were examined. The experiments were performed three times and a representative experiment is shown.
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