Forepaw Sensorimotor Deprivation in Early Life Leads to the Impairments on Spatial Memory and Synaptic Plasticity in Rats

<table>Morris water maze performance in forepaw sensorimotor deprived group (treatment) and sham-operated control group (control) at indicated age. (a) Escape latency for PN25 during training sessions, (b) PN35, (c) PN45, (d) PN60, (e) Swimming speed, and (f) The time spent in searching the targeted quadrant in the probe test for all groups. Data are presented as means ± S.E.M. <svg height="17.825001" id="M32" style="vertical-align:-3.27605pt" version="1.1" viewbox="0 0 71.775002 17.825001" width="71.775002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> a significant difference between groups for a given age (<svg height="11.375" id="M33" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 56.212502 11.375" width="56.212502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>). Number of rats (<svg height="7.9499998" id="M34" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 8.6625004 7.9499998" width="8.6625004" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>) is indicated in the figure.</table>

BioMed Research International

fig2

Figure 2

Figure 2: Forepaw Sensorimotor Deprivation in Early Life Leads to the Impairments on Spatial Memory and Synaptic Plasticity in Rats 