Research Article
Quantification of Spatial Parameters in 3D Cellular Constructs Using Graph Theory
Table 3
Quantitative metrics for 3.0
10
5 cells/mL collagen I hydrogel 24-hour timecourse.
| | Time (hours) | | 0 | 1 | 2 | 6 | 10 | 16 | 24 |
| | Average degree | 1.18 | 1.53 | 2.45 | 3.62 | 5.56 | 9.40 | 14.40 | | Clustering Coefficient | 0.26 | 0.37 | 0.47 | 0.56 | 0.63 | 0.59 | 0.61 | | Average eccentricity | 1.11 | 2.08 | 2.16 | 4.27 | 13.52 | 14.38 | 14.24 | | Maximum eccentricity (diameter) | 5.00 | 8.00 | 7.00 | 9.00 | 23.00 | 20.00 | 19.00 | | Minimum eccentricity (radius) | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 10.00 | 10.00 | | Average eccentricity 90 | 1.11 | 1.89 | 2.16 | 3.77 | 11.28 | 10.97 | 11.28 | | Maximum eccentricity 90 | 5.00 | 7.00 | 7.00 | 8.00 | 20.00 | 16.00 | 17.00 | | Minimum eccentricity 90 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 8.00 | 8.00 | | Average path length (closeness) | 0.84 | 1.31 | 1.41 | 2.39 | 6.97 | 7.07 | 7.36 | | Hop plot exponent | 0.20 | 0.49 | 0.41 | 0.70 | 1.08 | 1.51 | 1.46 | | Effective hop diameter | 14410546.75 | 961.44 | 3191.99 | 164.88 | 26.67 | 10.34 | 11.29 | | Giant connected ratio | 0.13 | 0.22 | 0.20 | 0.20 | 0.68 | 0.99 | 1.00 | | Number of connected components | 35.00 | 34.00 | 35.00 | 26.00 | 12.00 | 3.00 | 1.00 | | Percentage of isolated points | 0.38 | 0.32 | 0.22 | 0.05 | 0.02 | 0.01 | 0.00 | | Percentage of end points | 0.28 | 0.19 | 0.17 | 0.12 | 0.05 | 0.02 | 0.01 | | Number of central points | 23.00 | 23.00 | 21.00 | 9.00 | 11.00 | 1.00 | 14.00 | | Percentage of central points | 0.38 | 0.32 | 0.22 | 0.05 | 0.05 | 0.00 | 0.03 |
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