Table 2: Comparison of amino acid motifs which are responsible for the potent effects and characterisation of some published venom serine proteases with the four EoSP cDNAs.

Amino acidTSV-PABatroxobinAncrodEoSP-1EoSP-17EoSP-3EoSP-7References

H/RH57H57H57H67H67H67R67 Braud et al. [57]
DD102D102D102D112D112D112D112
SS195S195S195S208S208S208T208
HH192G192N192K205L205K205K205

FF193G193S193G206G206G206A206 Guinto et al. [58]
DD189D189D189G202D202G202D202
PP225P225P225P235P235P235P235

PP219P219P219P228V228P228P228Braud et al. [57]

DD96N96R96Y106Y106Y106Y106 Lee and Zhang [47]
DD97V97T97T107T107T107T107
EE98I98S98L108L108K108R108

HDS: Catalytic Traid; H/F: substrate specificity; D & P: Architecture of water channel; P: Evolutionary region to kallikrein; DDE: substrate specificity to plasminogen.