Research Article

Bioimaging of Nucleolin Aptamer-Containing 5-(N-benzylcarboxyamide)-2′-deoxyuridine More Capable of Specific Binding to Targets in Cancer Cells

Figure 2

Fluorescence analysis of Cy3-(5-BzdU)-modified-AS1411 compounds targeting C6 cells. The fluorescence of the 47 different Cy3-(5-BzdU)-modified-AS1411 compounds that were bound and targeted the nucleolin protein in the C6 cells was quantified. The 𝑋 -axis indicates numbers of compounds. AS represents the Cy3-labeled AS1411 and Mt the mutant form of the original AS1411 labeled with Cy3. These data are presented as the means ± SD calculated from quadruple wells. All fluorescence data were obtained at an excitation of 535 nm and emission of 570 nm.