Research Article

Bioimaging of Nucleolin Aptamer-Containing 5-(N-benzylcarboxyamide)-2′-deoxyuridine More Capable of Specific Binding to Targets in Cancer Cells

Figure 3

Confocal microscopy imaging of the Cy3-(5-BzdU)-modified-AS1411 targeting the C6 cells. numbers 29, 41, 12, and 26, Cy3-AS1411, and the mutant form of AS1411 labeled with Cy3 were visualized in the C6 cells. The confocal images were magnified to 200x. The nucleus was stained by DAPI (emission: 460 nm, blue color) and fluorescent imaging of the targeting of the C6 cells was visualized by a red color. Fluorescence images were acquired at an excitation of 535 nm and emission of 570 nm.
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