BALB/c Mice Vaccinated with Leishmania major Ribosomal Proteins Extracts Combined with CpG Oligodeoxynucleotides Become Resistant to Disease Caused by a Secondary Parasite Challenge
Analysis of the cellular responses. At week seven after ear infection the level of IFN- (a), IL-10 (b), and IL-4 (c) was measured by ELISA in the supernatants of spleen and retromaxillar lymph node cells cultures from both mice groups. Cells were in vitro stimulated for 48 hours with 12 g/ml of SLA or LRP and medium alone. Results are expressed as the mean±SD of twelve ears and DLN. (*).
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