A Human Recombinant Autoantibody-Based Immunotoxin Specific for the Fetal Acetylcholine Receptor Inhibits Rhabdomyosarcoma Growth In Vitro and in a Murine Transplantation Model
Figure 5
In vivo effect of scFv35-ETA on RD embryonal RMS cells (5 106 RD cells per mouse) transplanted subcutaneously into SCID mice. The first intraperitoneal immunotoxin injection (10 g twice daily) was carried out 2 days after the injection of tumor cells and repeated daily until day 10.