A Human Recombinant Autoantibody-Based Immunotoxin Specific for the Fetal Acetylcholine Receptor Inhibits Rhabdomyosarcoma Growth In Vitro and in a Murine Transplantation Model

Table 1

Comparison of IC₅₀ values of scFv35-ETA and mock-ETA control on various cell lines.

	Mean IC50 (nM)
	TE-671	RD	FL-OH-1	Ax-OH-1	RH-30	U937	A-204
scFv35-ETA	34	1.5	0.13	14	113	>500	>500
mock-ETA	113	22	12	90	>500	>500	>500

IC₅₀ values indicating concentrations required to achieve a 50% reduction of protein synthesis relative to untreated control cells as derived from colorimetric XTT assay in Figure 3.