Research Article

Evaluation of Cytotoxicity and Genotoxicity of Inula viscosa Leaf Extracts with Allium Test

Table 3

Chromosome and mitotic aberrations in the root meristem cells of 𝐴 𝑙 𝑙 𝑖 𝑢 𝑚 𝑐 𝑒 𝑝 𝑎 after 𝐼 . 𝑣 𝑖 𝑠 𝑐 𝑜 𝑠 𝑎 leaf extract treatment.

Treatment groupsConcentrationsChromosome breaks (%) ± SDStickiness (%) ± SDPolar deviations (%) ± SDAberrant cell (%) ± SDMNC () ± SD

Negative controlTap water0.69 ± 0.917.65 ± 1.978.34 ± 1.850.28 ± 0.18
Positive control (EMS) 2 × 1 0 2  M31.63 ± 12.88*8.97 ± 6.1840.60 ± 9,94*0.68 ± 0.18
Inula12.5 mg/ml7.22 ± 2.6117.32 ± 2.52*6.09 ± 1.3630.63 ± 5.03*0.64 ± 0.17
Inula25 mg/ml0.95 ± 0.9128.74 ± 8.18*10.14 ± 1.3339.83 ± 7.10*0.48 ± 0.41
Inula310 mg/ml8.89 ± 1.44*9.44 ± 12.9618.33 ± 6.93*0.04 ± 0.08*

* P < .05 in One Way ANOVA.