Research Article
Evaluation of Cytotoxicity and Genotoxicity of Inula viscosa Leaf Extracts with Allium Test
Table 3
Chromosome and mitotic aberrations in the root meristem cells of after leaf extract treatment.
| Treatment groups | Concentrations | Chromosome breaks (%) ± SD | Stickiness (%) ± SD | Polar deviations (%) ± SD | Aberrant cell (%) ± SD | MNC (‰) ± SD |
| Negative control | Tap water | — | 0.69 ± 0.91 | 7.65 ± 1.97 | 8.34 ± 1.85 | 0.28 ± 0.18 | Positive control (EMS) | M | — | 31.63 ± 12.88* | 8.97 ± 6.18 | 40.60 ± 9,94* | 0.68 ± 0.18 | Inula1 | 2.5 mg/ml | 7.22 ± 2.61 | 17.32 ± 2.52* | 6.09 ± 1.36 | 30.63 ± 5.03* | 0.64 ± 0.17 | Inula2 | 5 mg/ml | 0.95 ± 0.91 | 28.74 ± 8.18* | 10.14 ± 1.33 | 39.83 ± 7.10* | 0.48 ± 0.41 | Inula3 | 10 mg/ml | — | 8.89 ± 1.44* | 9.44 ± 12.96 | 18.33 ± 6.93* | 0.04 ± 0.08* |
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*
P < .05 in One Way ANOVA.
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