Research Article

Activation-Induced T Helper Cell Death Contributes to Th1/Th2 Polarization following Murine Schistosoma japonicum Infection

Table 1

Worm burdens and eggs counts in the livers of infected mice orally treated with or without artesunate.

0 d23 d23 d35 d35 d56 d56 d
artesunateartesunateartesunate

Adult worms0 9 . 7 5 ± 0 . 9 6 0 1 0 . 5 ± 1 . 2 9 0 1 0 ± 1 . 6 3 0
Liver eggs (/g)000 2 6 6 5 0 . 3 3 ± 1 9 1 2 . 9 5 0 5 1 1 8 4 . 5 8 ± 1 6 6 3 . 2 6 0

Mice were percutaneously infected with S. japonicum; some were orally administered artesunate as described in Section 2. At 0 (before infection) and 23, 35, and 56 days postinfection, six mice from each group were sacrificed for worm burdens and eggs counts measurements. 𝑃 < . 0 0 1 compared to the artesunate groups at same time point.