BioMed Research International / 2010 / Article / Fig 4

Research Article

Autocrine, Not Paracrine, Interferon-Gamma Gene Delivery Enhances Ex Vivo Antigen-Specific Cytotoxic T Lymphocyte Stimulation and Killing

Figure 4

Transduction efficiency of AAV delivery into DC and T cells by intracellular staining. Cells were infected as described in Section 2 and analyzed by intracellular staining for IFN-γ. (a) shows the results from DC infection. (b) shows the results from T cell infection. Note that both AAV/IFN-γ transduced DC and T cells demonstrate high levels of IFN-γ expression, but that T cells exhibit a signifiucant basal level of expression.

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.