Research Article

Genetic Immunization with CDR3-Based Fusion Vaccine Confers Protection and Long-Term Tumor-Free Survival in a Mouse Model of Lymphoma

Table 2

Therapeutic vaccination induces life span prolongation.

Mice groupVaccine formulationSurvival %Log-rank P-values versus
(n./tot)Group CGroup B
Day 15Day 22Day 28

ApTT V H CDR3/pTT V L CDR31005050 0 . 0 8 3 0 . 1 1 5
(6/6)(3/6)(3/6)

BpTT1000 0 . 4 0 8
(6/6)(0/6)

CUnimmunized800
(4/5)(0/5)