Development of a FLIPR Assay for the Simultaneous Identification of MrgD Agonists and Antagonists from a Single Screen

<table>Concentration response for beta-alanine, GABA, and glycine on rat MrgD receptor in CHO-DUKX cells. Representative data from calcium mobilization FLIPR assay performed in 384 wells are shown. Each data point represents mean of 32 replicates, and error bar represents SD. Human MrgD expressing CHO-DUKX cells also had similar dose response (data not shown).</table>

BioMed Research International

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Figure 1

Figure 1: Development of a FLIPR Assay for the Simultaneous Identification of MrgD Agonists and Antagonists from a Single Screen 