Research Article

Evaluation of Hepcidin Isoforms in Hemodialysis Patients by a Proteomic Approach Based on SELDI-TOF MS

Table 1

Clinical features and baseline laboratory data.

HD patientsControls

Number of patients5457
Gender (Male/Female)29/2538/21
Age (years)67 ± 1435 ± 15
HFE genotype
 wt/wt ( 𝑛 )35
 H63D/wt ( 𝑛 )14
 C282Y/wt ( 𝑛 )2
Hemoglobin (g/dL)11.4 ± 1.014.4 ± 1.2
Iron ( 𝜇 g/dL)45.2 (43.1−60.0)96.4 (89.1–104.2)
Transferrin Saturation (%)20.5 ± 8.328.9 ± 9.0
Ferritin (ng/mL)174 (156−258)90 (47−149)
CRP (mg/dL)4.7 (5.0−8.9)0.8 (0.4−1.4)
Interleukin-6 (pg/mL)6.8 ± 5.8*

R e f e r e n c e range in normal subjects = 0.2–3.2 pg/mL.