Improved Killing of Human High-Grade Glioma Cells by Combining Ionizing Radiation with Oncolytic Parvovirus H-1 Infection

Table 1

Long-term effect of ionizing radiation (IR) and/or parvovirus H-1 (H-1PV) infection on human high-grade glioma cells cultures.

cell line	IR	H-1PV	1 week p.i.	2 weeks p.i.	3 weeks p.i.
NCH-37	0	MOCK	++++	++++	++++
	0	MOI 5	+	++	+++
	20	MOCK	+	++	++
	20	MOI 5	+	+	0
NCH-82	0	MOCK	++++	++++	++++
	0	MOI 5	+	++	++
	20	MOCK	+	++	++
	20	MOI 5	+	+	0
NCH-89	0	MOCK	++++	++++	++++
	0	MOI 5	+	++	++
	20	MOCK	+	+	++
	20	MOI5	+	+	0

(++++) confluent cell layer.
(+++) conflating cell clones.
(++) single cell clones.
(+) single cells.
(0) no cells.