Research Article
Acute, Multiple-Dose Dermal and Genetic Toxicity of Nu-3: A Novel Antimicrobial Agent
Table 4
CHO/HGPRT mutation assay.
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Mutation frequency (mutants/1 × 106 clonable cells) | Groups | Activated | Nonactivated |
| Saline control | 3.30 | 3.30 | Positive control | 244.0 | 187.0 | Nu-3 (500 g/ml) | 5.40 | 4.50 | Nu-3 (1000 g/ml) | 4.50 | 5.70 | Nu-3 (2000 g/ml) | 6.90 | 8.30 |
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