Research Article
Detection of Fetomaternal Genotype Associations in Early-Onset Disorders: Evaluation of Different Methods and Their Application to Childhood Leukemia
Table 3
Parental genotype distributions under mating symmetry and mating asymmetry.
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Alleles for a biallelic locus are denoted 1 and 2 and the corresponding genotypes 11, 12 or 22. indicates the number of individuals in the sample; the th mating type probability under the assumption of random mating; the mating-pair disequilibrium for the th parental couple. is a multiplicative factor between 0 and 2 that describes the over representation (1), under representation (1) or symmetry (=1) of a mate-pair combination in the corresponding th mating type. |