|
| Symbol | Entrez Gene Name | Networks |
|
| Cytokines | CD40LG | CD40 ligand | 38 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 12 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 36 |
| IL2 | interleukin 2 | 2, 29, 37 |
| IL4 | interleukin 4 | 29, 32, 37 |
| IL6 | interleukin 6 (interferon, beta 2) | 29 |
| IL8 | interleukin 8 | 28, 31 |
| IL18 | interleukin 18 (interferon-gamma-inducing factor) | 29 |
| SPP1 | secreted phosphoprotein 1 | 23, 46 |
| TNF | tumor necrosis factor (TNF superfamily, member 2) | 26, 29, 30, 33, 37, 38, 40, 41, 45 |
|
| Enzymes | CNTN1 | contactin 1 | 23 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 5, 36 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 5 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 5 |
| FN1 | fibronectin 1 | 7, 28 |
| GNAS | GNAS complex locus | 41 |
| GSTP1 | glutathione S-transferase pi 1 | 49 |
| HINT1 | histidine triad nucleotide binding protein 1 | 48 |
| KRAS | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 3 |
| PDE4A | phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) | 44 |
| PDE4D | phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila) | 41 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 7, 28 |
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 5 |
| RAP1B | RAP1B, member of RAS oncogene family | 23 |
| REV3L | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 39 |
| RRM1 (includes EG:6240) | ribonucleotide reductase M1 | 26 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 26 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 42, 48 |
| Growth Factors | ANGPT2 | angiopoietin 2 | 7 |
| CTGF | connective tissue growth factor | 2, 36, 40 |
| FGF2 | fibroblast growth factor 2 (basic) | 23, 31 |
| INHBA | inhibin, beta A | 45 |
| LEP | leptin | 6 |
| TGFB1 | transforming growth factor, beta 1 | 20, 26, 33, 35, 40, 45 |
| VEGFA | vascular endothelial growth factor A | 29, 30 |
|
| Ion Channels | PKD1 | polycystic kidney disease 1 (autosomal dominant) | 45 |
| PKD2 (includes EG:5311) | polycystic kidney disease 2 (autosomal dominant) | 45 |
|
| Kinases | CDC2 | cell division cycle 2, G1 to S and G2 to M | 32, 36 |
| CSF1R | colony stimulating factor 1 receptor | 3, 34 |
| EGFR | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 28 |
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 27, 30, 33, 35, 38, 40, 45, 47 |
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 2 |
| INSR | insulin receptor | 26 |
| JAK1 | Janus kinase 1 (a protein tyrosine kinase) | 37 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 9 |
| MAPK4 | mitogen-activated protein kinase 4 | 17 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 45 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 42 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 11 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 11 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 17 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 16 |
| STC1 | stanniocalcin 1 | 49 |
| WEE1 | WEE1 homolog (S. pombe) | 18 |
|
| Ligand-Dependent Nuclear Receptors | AHR | aryl hydrocarbon receptor | 44 |
| AR | androgen receptor | 30 |
| ESR1 | estrogen receptor 1 | 5, 30, 44 |
| ESR2 | estrogen receptor 2 (ER beta) | 44 |
| PPARG | peroxisome proliferator-activated receptor gamma | 12, 29 |
|
| Peptidases | HPR (includes EG:3250) | haptoglobin-related protein | 24 |
| MEST | mesoderm specific transcript homolog (mouse) | 18 |
| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72 kDa gelatinase, 72 kDa type IV collagenase) | 11 |
|
| Phosphatases | DUSP1 | dual specificity phosphatase 1 | 3 |
| PPP3R1 | protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform | 24 |
| PTEN | phosphatase and tensin homolog | 19 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 22 |
|
| Transcription Regulators | BCL6 | B-cell CLL/lymphoma 6 | 16 |
| BRCA1 | breast cancer 1, early onset | 5, 30, 42 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 11 |
| CREB1 | cAMP responsive element binding protein 1 | 6 |
| EGR1 | early growth response 1 | 6, 26, 35 |
| EMX2 | empty spiracles homeobox 2 | 15 |
| FOS | v-fos FBJ murine osteosarcoma viral oncogene homolog | 6, 35, 49 |
| FOXO1 | forkhead box O1 | 3 |
| GATA3 | GATA binding protein 3 | 2 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 10, 31, 44, 47 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 47, 50 |
| JUN | jun oncogene | 49 |
| JUNB | jun B proto-oncogene | 11, 47 |
| NRIP1 | nuclear receptor interacting protein 1 | 36 |
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 44 |
| SMAD6 | SMAD family member 6 | 14 |
| SMAD7 | SMAD family member 7 | 11 |
| SP2 | Sp2 transcription factor | 31 |
| TP53 | tumor protein p53 | 22, 27, 32, 34, 36, 37, 40, 41, 45 |
| WT1 | Wilms tumor 1 | 7 |
| ZFP36 | zinc finger protein 36, C3H type, homolog (mouse) | 20 |
|
| Transmembrane Receptors | IL2RG | interleukin 2 receptor, gamma (severe combined immunodeficiency) | 37 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 11, 28, 30 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 7 |
| ITGB4 | integrin, beta 4 | 30 |
|
| Transporters | APOE | apolipoprotein E | 36 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 41 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 | 21 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter, taurine), member 6 | 1 |
|
| Others | ACTB | actin, beta | 9, 49 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 24 |
| BCL2 | B-cell CLL/lymphoma 2 | 3, 48 |
| BIRC5 | baculoviral IAP repeat-containing 5 | 36 |
| BSG | basigin (Ok blood group) | 41 |
| CAV2 | caveolin 2 | 5 |
| CCNA2 | cyclin A2 | 43 |
| COL18A1 | collagen, type XVIII, alpha 1 | 47 |
| DCN | decorin | 28 |
| EPS15 | epidermal growth factor receptor pathway substrate 15 | 28 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 45 |
| EZR | ezrin | 18 |
| FBN1 | fibrillin 1 | 36 |
| IRS2 | insulin receptor substrate 2 | 6, 37 |
| ITGA6 | integrin, alpha 6 | 30 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 6 |
| MARCKS (includes EG:4082) | myristoylated alanine-rich protein kinase C substrate | 47 |
| SDC2 | syndecan 2 | 8 |
| TAL1 | T-cell acute lymphocytic leukemia 1 | 18 |
| THBS2 | thrombospondin 2 | 11 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 11 |
| TMSB10 | thymosin beta 10 | 19 |
| TRAF2 | TNF receptor-associated factor 2 | 26 |
| VIM | vimentin | 19, 36 |
|
