Differential Expression of MicroRNAs between Eutopic and Ectopic Endometrium in Ovarian Endometriosis

Table 6

KEGG pathways containing the predicted targets of the differentially expressed miRNAs. Pathway-Express analysis identified the KEGG molecular pathways affected by the predicted targets of the differentially expressed miRNAs. 𝑃<.05.

Rank	Pathway name	Genes in pathway	Input genes in pathway	Pathway genes on chip	𝑃-value
1	MAPK signaling pathway	272	103	197	3.23E−08
2	Axon guidance	129	67	113	3.23E−08
3	Melanogenesis	102	48	74	8.60E−08
4	Pathways in cancer	330	119	245	2.27E−07
5	Regulation of actin cytoskeleton	217	78	158	2.31E−05
6	Focal adhesion	203	75	150	2.31E−05
7	Wnt signaling pathway	152	63	127	1.60E−04
8	Glioma	65	30	50	2.94E−04
9	GnRH signaling pathway	103	36	65	4.86E−04
10	Renal cell carcinoma	69	34	61	5.92E−04
11	Insulin signaling pathway	138	49	98	7.02E−04
12	Adherens junction	78	34	62	7.65E−04
13	TGF-beta signaling pathway	87	38	72	8.49E−04
14	Prostate cancer	90	36	68	.0011
15	ECM-receptor interaction	84	30	55	.0016
16	Phosphatidylinositol signaling system	76	30	55	.0016
17	Calcium signaling pathway	182	54	115	.0016
18	Colorectal cancer	84	36	70	.0018
19	Long-term potentiation	73	31	58	.0018
20	Adipocytokine signaling pathway	67	27	50	.0032
21	ErbB signaling pathway	87	34	69	.0056
22	Pancreatic cancer	72	30	59	.0056
23	Gap junction	96	33	67	.0063
24	Type II diabetes mellitus	45	18	31	.0069
25	Small cell lung cancer	86	30	61	.0095
26	Thyroid cancer	29	14	23	.0111
27	Ubiquitin mediated proteolysis	138	42	94	.0145
28	Long-term depression	75	24	49	.0225
29	Non-small cell lung cancer	54	20	39	.0225
30	Acute myeloid leukemia	59	22	45	.0304
31	Melanoma	71	25	53	.0323
32	Cardiac muscle contraction	87	20	41	.0402
33	Chronic myeloid leukemia	75	28	62	.0410