BioMed Research International / 2010 / Article / Tab 4

Research Article

Computational Method for Estimating DNA Copy Numbers in Normal Samples, Cancer Cell Lines, and Solid Tumors Using Array Comparative Genomic Hybridization

Table 4

Frequent amplifications with CN  > 9 observed in 178 cancer cell lines. Chromosomal positions are based on March 2006 version of the UCSC Human Genome Browser.

RegionNumber of observationsLikely oncogene

chr8:81240524-819743705TPD52
chr8:113091665-11474234210*
chr8:128756816-12884911317MYC
chr8:142078709-1421077817**PTK2
chr11:68619900-6998544811CTTN, FGF4, FGF3, FGF19, ORAOV1, CCND1, MYEOV
chr17:34999505-3526434114ERBB2
chr17:43477124-4479546510
chr17:55677511-611493116APPBP2, PPM1D, BCAS3
chr20:45554593-460543385NCOA3
chr20:55503756-562413755
chr20:57622421-586039456
chr22:19057363-201309555CRKL

One of these amplifications also involves MYC.
Two of these amplifications also involve MYC.

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