Computational Method for Estimating DNA Copy Numbers in Normal Samples, Cancer Cell Lines, and Solid Tumors Using Array Comparative Genomic Hybridization
Table 4
Frequent amplifications with CN observed in 178 cancer cell lines. Chromosomal positions are based on March 2006 version of the UCSC Human Genome Browser.
Region
Number of observations
Likely oncogene
chr8:81240524-81974370
5
TPD52
chr8:113091665-114742342
10*
chr8:128756816-128849113
17
MYC
chr8:142078709-142107781
7**
PTK2
chr11:68619900-69985448
11
CTTN, FGF4, FGF3, FGF19, ORAOV1, CCND1, MYEOV
chr17:34999505-35264341
14
ERBB2
chr17:43477124-44795465
10
chr17:55677511-61149311
6
APPBP2, PPM1D, BCAS3
chr20:45554593-46054338
5
NCOA3
chr20:55503756-56241375
5
chr20:57622421-58603945
6
chr22:19057363-20130955
5
CRKL
One of these amplifications also involves MYC. Two of these amplifications also involve MYC.
