Association of Combined Maternal-Fetal TNF-𝛼 Gene G308A Genotypes with Preterm Delivery: A Gene-Gene Interaction Study

Table 5

Association of combined maternal-fetal TNF-𝛼 G308A genotypes with preterm delivery.

Genotypes*		Preterm delivery
Child	Mother	RR	95%CI
GG	GG^†	1.00
GG	GA	0.36	0.14–0.96^§
GA	GG	0.25	0.03–1.95
GA	GA	0.20	0.07–0.58^§
GA	AA	1.12	0.41–3.10
AA	GA	0.82	0.30–2.24
AA	AA	0.59	0.15–2.25

*: Use LRTs, comparing the model with an interaction term for combined maternal-fetal genotypes against the model with maternal genotype and fetal genotype only (without interaction term).
^†: Reference category.
^§: Significant.