Table of Contents Author Guidelines Submit a Manuscript
Journal of Biomedicine and Biotechnology
Volume 2010 (2010), Article ID 485306, 9 pages
Research Article

Testosterone Depletion by Castration May Protect Mice from Heat-Induced Multiple Organ Damage and Lethality

1The Institute of Basic Medical Sciences, National Cheng Kung University School of Medicine, Tainan, Taiwan
2Department of Pharmacy, Chia-Nan University of Pharmacy and Science, Tainan, Taiwan
3Department of Medical Research, Chi Mei Medical Center, Tainan, Taiwan
4Department of Obstetrics and Gynecology, Chi Mei Medical Center, Southern Taiwan University, Tainan, Taiwan
5Department of Biotechnology, Southern Taiwan University, Tainan, Taiwan

Received 1 December 2009; Accepted 3 February 2010

Academic Editor: Rene Anand

Copyright © 2010 Chian-Yuh Lin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [12 citations]

The following is the list of published articles that have cited the current article.

  • Turker Topcu, and Francis Robicheaux, “Multiphoton population transfer in systems violating the classical twist condition: A comparative study of separatrix crossing in phase space,” Physical Review E, vol. 83, no. 4, 2011. View at Publisher · View at Google Scholar
  • Chian-Yuh Lin, Chuan-Chih Hsu, Mao-Tsun Lin, and Sheng-Hsien Chen, “Flutamide, an androgen receptor antagonist, improves heatstroke outcomes in mice,” European Journal of Pharmacology, vol. 688, no. 1-3, pp. 62–67, 2012. View at Publisher · View at Google Scholar
  • A. Blake Buletko, Dean E. Dluzen, Janet L. McDermott, Altaf S. Darvesh, and Werner J. Geldenhuys, “Markers associated with testosterone enhancement of methamphetamine-induced striatal dopaminergic neurotoxicity,” Neurotoxicology and Teratology, vol. 34, no. 3, pp. 338–343, 2012. View at Publisher · View at Google Scholar
  • Damian G. Zuloaga, David L. Carbone, Alicia Quihuis, Ryoko Hiroi, David L. Chong, and Robert J. Handa, “Perinatal dexamethasone-induced alterations in apoptosis within the hippocampus and paraventricular nucleus of the hypothalamus are influenced by age and sex,” Journal of Neuroscience Research, vol. 90, no. 7, pp. 1403–1412, 2012. View at Publisher · View at Google Scholar
  • Leah Z. FitzGerald, Wendie A. Robbins, James S. Kesner, and Lin Xun, “Reproductive hormones and interleukin-6 in serious leisure male athletes,” European Journal of Applied Physiology, vol. 112, no. 11, pp. 3765–3773, 2012. View at Publisher · View at Google Scholar
  • Hongjuan Zhao, Alan Thong, Rosalie Nolley, Stephen W. Reese, Jennifer Santos, Alexandre Ingels, and Donna M. Peehl, “Patient-derived tissue slice grafts accurately depict response of high-risk primary prostate cancer to androgen deprivation therapy,” Journal of Translational Medicine, vol. 11, no. 1, 2013. View at Publisher · View at Google Scholar
  • Benjamin Ladeuix, Claude Duchamp, and Olivier Levillain, “Underestimated contribution of skeletal muscle in ornithine metabolism during mouse postnatal development,” Amino Acids, 2013. View at Publisher · View at Google Scholar
  • Sheng-Hsien Chen, Mao-Tsun Lin, and Ching-Ping Chang, “Ischemic and oxidative damage to the hypothalamus may be responsible for heat stroke,” Current Neuropharmacology, vol. 11, no. 2, pp. 129–140, 2013. View at Publisher · View at Google Scholar
  • Chuan-Chih Hsu, Sheng-Hsien Chen, Cheng-Hsien Lin, and Ming-Chi Yung, “Human recombinant factor VIIa may improve heat intolerance in mice by attenuating hypothalamic neuronal apoptosis and damage,” Apoptosis, vol. 19, no. 10, pp. 1484–1496, 2014. View at Publisher · View at Google Scholar
  • Katherine Mifflin, Curtis Benson, Kevin Thorburn, Glen B. Baker, and Bradley J. Kerr, “Manipulation of neurotransmitter levels has differential effects on formalin evoked nociceptive behaviour in male and female mice,” The Journal of Pain, 2015. View at Publisher · View at Google Scholar
  • Nicole Carrier, Xuezhen Wang, Linshan Sun, and Xin-Yun Lu, “Sex-Specific and Estrous Cycle-Dependent Antidepressant-Like Effects and Hippocampal Akt Signaling of Leptin,” Endocrinology, vol. 156, no. 10, pp. 3695–3705, 2015. View at Publisher · View at Google Scholar
  • Maria Bergquist, Fredrik Huss, Filip Fredén, Göran Hedenstierna, Johanna Hästbacka, Alan L. Rockwood, Mark M. Kushnir, and Jonas Bergquist, “Altered adrenal and gonadal steroids biosynthesis in patients with burn injury,” Clinical Mass Spectrometry, vol. 1, pp. 19–26, 2016. View at Publisher · View at Google Scholar