Research Article

Regression of Human Prostate Tumors and Metastases in Nude Mice following Treatment with the Recombinant Oncolytic Vaccinia Virus GLV-1h68

Figure 4

Immunohistochemical staining of PC-3 tumors. Male ((a) and (b)) or female ((c) and (d)) mice bearing PC-3 tumors were i.v. injected either with PBS ((a) and (c)) or with 5 × 106 pfu of GLV-1h68 ((b) and (d)). At day 42 after injection, whole tumor cross-sections (100  𝜇 m) were labeled with Phalloidin-TRITC (red) and anti-VACV antibody (green). Scale bars = 5 mm.
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