Regression of Human Prostate Tumors and Metastases in Nude Mice following Treatment with the Recombinant Oncolytic Vaccinia Virus GLV-1h68

Figure 8

Immunohistochemistry staining of MHC class II positive cells in PC-3 tumors. (a) Forty-two days after GLV-1h68 administration PC-3 tumors were excised, sectioned, and labeled for MHCII. In addition, GFP signals from GLV-1h68-infected cells and transmission images are shown. (b) Overlay of MHCII and GFP signals in uninfected (left) and virus-infected PC-3 tumors (right). Scale bars = 5 mm.