Cytokine-Induced Monocyte Characteristics in SLE

Table 1

DAVID analysis of SLE gene expression.

Gene List	GO Term	Count	P value	Fold Enriched
SLE UP	Immune system process	45	6.46E-15	3.78
	Leukocyte activation	14	9.91E-06	4.60
	Cytokine receptor activity	5	1.11E-03	10.67
	Intracellular signaling cascade	32	3.73E-03	1.68
	Defense response	15	2.16E-02	1.94
AIFN UP	Immune system process	57	2.34E-23	4.59
	Response to virus	24	4.02E-22	16.68
	Defense response	33	1.14E-11	4.09
	Induction of apoptosis	10	5.04E-03	3.08
	Interferon type I production	3	7.90E-03	21.38
GIFN UP	Immune system process	63	2.08E-28	5.04
	Response to virus	17	5.98E-13	11.75
	Defense response	34	2.62E-12	4.19
	Regulation of apoptosis	20	4.35E-04	2.46
	Lymphocyte proliferation	7	6.09E-04	6.61
IL4 UP	Response to external stimulus	25	2.83E-05	2.59
	Ribosome biogenesis and assembly	8	3.25E-04	6.05
	Cell communication	72	3.46E-04	1.43
	Chemokine activity	6	5.24E-04	8.85
	Lymphocyte proliferation	6	4.13E-03	5.60