Nanofibers Offer Alternative Ways to the Treatment of Skin Infections

Table 1

Molecules and organisms encapsulated into electrospun nanofibers.

Encapsulated molecules	Polymer/polymer blends	Reference
Antibiotics
Rifampin	PLLA	[81]
Doxorubicin hydrochloride	PLLA	[81]
Paclitaxil	PLLA	[81]
Tetracycline hydrochloride	PEVA	[60]
Mefoxin	PLGA/PEG-b-PLLA	[82]
Plasmid DNA
pCMVb encoding a 𝛽-Galactosidase	PLGA and PLA-PEG	[83]
Growth Factors
Human 𝛽-nerve growth factor (NGF)	PCLEEP	[54]
Human glialcell-derived neurotrophic factor (GDNF)	PCLEEP	[84]
Bone morfogenetic protein-2 (BMP-2)	PLGA-Hap	[85]
Antimicrobial compounds
Silver nanoparticles	Cellulose acetate	[72]
	PCL/silver-loaded zirconium phosphate	[86]
Proteins
BSA	PEO	[87]
Lysozyme	PCL/PEO	[53]
Lysozyme	PCL/PEG	[77]
Cytochrome C	PLLA/PLL	[61]
Bacteria
Eschericia coli
Staphylococcus albus	PVA	[88]
Micrococcus luteus
Eschericia coli	PEO	[89]
Lactobacillus plantarum	PEO	[90]
Bacteriophages
T7
T4
𝜆	PVA	[88]
M13	PVP	[91]

PLLA: poly (L-lactide); PEVA: poly-ethylene-co-vinyl acetate; PLGA: poly-lactate-co-glycolide; PEG: polyethylene glycol; PLGA/PEG-b-PLLA: poly-lactate-co-glycolide/polyethylene glycol-block-poly(L lactide); PCL: poly ε-caprolactone; PCLEEP: poly ε-caprolactone ethyl ethylene phosphate; Hap: Hydroxyapatite; PEO: polyethylene oxide; PDLA: poly(D,L-lactide); PLL: poly(L-lysine); PVA: poly(vinyl alcohol); PVP: polyvinylpyrrolidone.