A Styrene-alt-Maleic Acid Copolymer Is an Effective Inhibitor of R5 and X4 Human Immunodeficiency Virus Type 1 Infection
Figure 1
Structures of alt-PSMA and PSS. (a) alt-PSMA (120,000 average MW) is a readily synthesized copolymer of styrene and maleic acid that incorporates two carboxylic groups and a phenyl group in each repeating unit. (b) The structure of poly(sodium 4-styrene sulfonate) (PSS), which includes a single, sulfated phenyl ring in each repeat unit, is shown for comparison.
