Osteogenic Activity of Locally Applied Small Molecule Drugs in a Rat Femur Defect Model
Figure 5
Histomorphometric Analysis of Bone Formation. Areas of new bone formation were measured from cross-sections of each femur defect. The total new bone area (a) was further categorized as being within the defect site and marrow space (b) or on the femur periphery (c). New bone area for each treatment group (gray bars) was compared to the new bone area in the contralateral, blank-treated femurs (black bars) for that group using Students -tests. Significant values are shown (low-dose, LD; high-dose, HD).
