𝛽-Glucan Oligosaccharide Enhances CD𝟖⁺ T Cells Immune Response Induced by a DNA Vaccine Encoding Hepatitis B Virus Core Antigen

Figure 2

Effect of 𝛽-glu6 on pB144-induced recruitment and activation of CD4⁺ T cells in the spleen. Mice were immunized with 𝛽-glu6 (G), pB144, pB144+G, or PBS as described in Section 2. Five days after priming and five days after boosting, the percentage of CD4⁺ T cells (a) and the number of CD4⁺/CD69⁺ T cells (b) in the spleen were evaluated. Data are expressed as mean of 3 mice/group. *𝑃<.05, pB144 + G versus pB144 alone.

(a)

(b)