Endocrine Disruptors and Leydig Cell Function

Table 1

Natural and synthetic chemicals affecting Leydig cell function.

Chemical	Proposed target	Application or source
Procymidone	Androgen receptor antagonist	Fungicide, control of plant diseases
Linuron	Androgen receptor antagonist	Herbicide, postemergence control of weeds in crops
Vinclozolin	Androgen receptor antagonist	Fungicide
p,p^DDT	Androgen receptor antagonist	Pesticide
Dioxins	Aryl hydrocarbon receptor agonist	By-product of chlorinated hydrocarbons
Phthalates	Peroxisome proliferator-activated receptors (PPARs)?	Plasticizers
Genistein	ERs stimulator	Soy-derived food
Resveratrol	ERs stimulator	Red wine, red grape
Bisphenol A	ERs stimulator	Synthesis of polycarbonate plastics

Corresponding references are present in the text.