Combination of Intensive Chemotherapy and Anticancer Vaccines in the Treatment of Human Malignancies: The Hematological Experience

Table 2

T cell reconstitution after autologous stem cell transplantation.

Immunocompetent cell	Time until reconstitution
Number of circulating CD4^+ T cells	1–5 years
Number of circulating CD8^+ T cells	3–12 months
T cell proliferation	3 months–5 years
T cell cytokine production	6 months–5 years
T cell response to exogenous IL2	7 months–5 years
Cytotoxic T cells	2 months–5 years

Adapted from article by Porrata et al. [60]. In general there is considerable variability in the data that have been found for T cell reconstitution, both in-between patients and studies. Thus, the timeframes indicate when the majority of patients can expect to reach normal values.