Research Article

Modulation of Muscle Atrophy, Fatigue and MLC Phosphorylation by MuRF1 as Indicated by Hindlimb Suspension Studies on MuRF1-KO Mice

Figure 6

Muscle Fatigue. We fatigued the soleus muscle by stimulating the soleus muscle at a submaximal frequency (60 Hz, inset of Figure 5(a)) every three seconds for a total of 100 stimuli. (a) The mean force of all muscles. (b) Force at the 105 second time point. There is a significant difference between the wt suspended and the MuRF1-KO suspended mice.
693741.fig.006a
(a)
693741.fig.006b
(b)