The Role of Genetic Variation Near Interferon-Kappa in Systemic Lupus Erythematosus

Table 1

Initial results for the IFNK region in the pooled genome-wide association study In African-American subjects.

Rank	RS ID	Position	SLE	Control	𝑃-Value (𝑍^2)	Gene
10579	rs2069031	27417257	0.24	0.18	.084533	MOBKL2B
25111	rs763372	27418665	0.37	0.33	.233357	MOBKL2B
30738	rs1058326	27437089	0.64	0.67	.295482	MOBKL2B
96108	rs10511817	27444173	0.74	0.74	.991276	MOBKL2B
58144	rs1822724	27446580	0.18	0.20	.587242	MOBKL2B
86908	rs10511816	27458461	0.12	0.13	.892110	MOBKL2B
29622	rs7866248	27464593	0.66	0.62	.282786	MOBKL2B
51	rs1031154	27488800	0.58	0.74	.000007	MOBKL2B
83966	rs2783009	27504584	0.27	0.27	.860562	MOBKL2B
30667	rs774354	27505967	0.66	0.62	.294678	MOBKL2B
44987	rs774353	27506436	0.33	0.35	.445904	MOBKL2B
51264	rs10511815	27508821	0.10	0.08	.513456	MOBKL2B
3058	rs700795	27510508	0.21	0.29	.016545	MOBKL2B
3280	rs3849944	27550594	0.45	0.37	.018332	C9orf72
13896	rs7864840	27573468	0.21	0.17	.117979
96358	rs590299	27591570	0.28	0.28	.993607
85694	rs634157	27598585	0.80	0.80	.878910

Rank: rank order of association in the study, as determined by 𝑃-value, position is listed in base pairs on chromosome 9. “SLE” and “Control” indicate the calculated allele frequencies in SLE patients and controls, respectively.