Impaired Skeletal Muscle Repair after Ischemia-Reperfusion Injury in Mice

Table 1

Cytokine expressed in the ischemic-reperfused and myotoxin-treated muscles at day 7.

	IR+ (% uninjured)	MI+ (% uninjured)
Myogenesis
IGF-I	71	63
IGF-II	43	64
IGFBP-2	65	65
IGFBP-3	107	122
IGFBP-5	109	126
IGFBP-6	109	110
bFGF	106	97
HGF R	0	19
Angiogenesis
VEGF	132	113
VEGF R1	103	138
VEGF R2	0	0
VEGF R3	0	0
VEGF-D	0	0
ECM remodelling
MMP-2	65	153
MMP-3	87	52
TIMP-1	93	85
TIMP-2	96	73
Pro-MMP-9	44	48
Chemokines
Fractalkine	111	90
GCSF	95	91
GM-CSF	91	97
KC (IL8)	129	113
MCP1	75	85
MCP-5	72	79
MIP-1_	136	104
MIP-1_	196	135
MIP-2	146	119
MIP-3 _	153	113
MIP-3_	132	118
RANTES	119	141
Inflammation
IL-1 b	117	94
IL-6	89	69
TNF_	107	92
sTNF RI	146	94
sTNF RII	135	102