Review Article

Titin Diversity—Alternative Splicing Gone Wild

Figure 3

Exon inclusion in clones from the human titin PEVK region. Data from left ventricle samples of five different individuals—three normal (NH-1, NH-2, NH-3), one restrictive cardiomyopathy (RCM), and one dilated cardiomyopathy (DCM). Exon number is listed across the top. Filled boxes denote exon inclusion. Letter designations in each block refer to separate clones from each individual. Clones were obtained by PCR amplification after RT-PCR using primers from exons 108 and 225. Full details on the methods have been published [38]. Data from sample NH-1 is from [38] and for NH-2 clones from [37].
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