Research Article

Effects of Sizes and Conformations of Fish-Scale Collagen Peptides on Facial Skin Qualities and Transdermal Penetration Efficiency

Figure 2

Cell proliferation and collagen release in embryonic skin fibroblast cell lines treated by FSCPs. Comparisons of the proliferation activity (a) and procollagen synthesis ability (b) on Detroit 551 cells (human embryonic skin fibroblast line) and STO cells (mouse embryonic fibroblast) treated with 0, 0.4, 0.8, 1.6, 3.2, 6.3, 12.5, 25, 50, 100, and 200 mM FSCPs. The group with no FSCPs acts as a control. After 48 hours posttreatment, the samples were analyzed by MTT and procollagen type I C-peptide ELISA assays. Bars stand as means ± standard deviation (triplicate for each group).
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(a)
757301.fig.002b
(b)