Research Article

Diclofenac-Induced Apoptosis in the Neuroblastoma Cell Line SH-SY5Y: Possible Involvement of the Mitochondrial Superoxide Dismutase

Figure 2

Effect of diclofenac on the intracellular ROS level. SH-SY5Y cells were incubated with vehicle alone (white bars) or 150  𝜇 M diclofenac (black bars) for the indicated times. The intracellular ROS level was evaluated through the usage of the fluorescent probe DCFH-DA, as described in Section 2.5. Fluorescence intensity was reported as Arbitrary Units (AU); * 𝑃 < . 0 1 compared to untreated cells.
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