Diclofenac-Induced Apoptosis in the Neuroblastoma Cell Line SH-SY5Y: Possible Involvement of the Mitochondrial Superoxide Dismutase
Figure 2
Effect of diclofenac on the intracellular ROS level. SH-SY5Y cells were incubated with vehicle alone (white bars) or 150 M diclofenac (black bars) for the indicated times. The intracellular ROS level was evaluated through the usage of the fluorescent probe DCFH-DA, as described in Section 2.5. Fluorescence intensity was reported as Arbitrary Units (AU); * compared to untreated cells.