Receptor-Mediated and Fluid-Phase Transcytosis of Horseradish Peroxidase across Rat Hepatocytes
Figure 2
Kinetics of biliary secretion of HRP in the absence of mannan in the perfused rat liver. Isolated livers were perfused with HRP (0,8 mg/mL) for 1 minute at 37°C (time 0) followed by a single pass perfusion with marker-free KHB at 37°C. The amount of HRP in single bile drops was determined and the secretion rate was calculated (a) based on the bile flow (b). Data shown are the mean SD five perfusions. (c) The total amount of HRP (cummulative HRP secretion) secreted into bile as a function of the perfusion time is shown.
